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Integrase strand transfer inhibitor ( INSTI ) resistance profiles and factors associated with resistance in antiretroviral-naive and -experienced patients failing an INSTI-based regimen in clinical pr ...


The aim of a study was to expand understanding of the virological potency of initial Dolutegravir plus Lamivudine dual therapy ( Dolutegravir / Lamivudine; Dovato ). Researchers have compared the vir ...


The FDA ( US Food and Drug Administration ) has approved a new drug for the treatment of influenza. Baloxavir marboxil ( Xofluza ) works against the two types of influenza virus that cause disease in ...


The results from a multi-arm phase 2 clinical trial evaluating Grazoprevir / Elbasvir ( MK-5172 / MK-8742, the investigational NS3/4A protease inhibitor and NS5A inhibitor, respectively ) with or wit ...


Data from the ALLY trial investigating a Ribavirin-free 12-week regimen of Daclatasvir ( DCV ) in combination with Sofosbuvir ( SOF ) in genotype 3 hepatitis C ( HCV ) patients, a patient population t ...


Results from studies in chronic hepatitis C patients with human immunodeficiency virus type 1 ( HIV-1 ) co-infection ( TURQUOISE-I ) and liver transplant recipients ( CORAL-I ) were presented at The L ...


A commonly-used HIV drug has been shown to kill off the human papillomavirus ( HPV ) that leads to cervical cancer in a world-first clinical trial. Researchers have examined Kenyan women diagnosed w ...


Researchers have successfully treated the deadly Ebola virus in infected animals following onset of disease symptoms, according to a report published in Science Translational Medicine. The results s ...


Short-course antiretroviral therapy ( ART ) in primary human immunodeficiency virus ( HIV ) infection may delay disease progression but has not been adequately evaluated.Researchers randomly assigned ...


Interim data presented recently have shown that all patients ( 13/13 ) who reached their 4-weeks post-treatment follow-up have undetectable levels of hepatitis C virus ( SVR4 ) after completing a 12-w ...


Planning for outbreaks of influenza is a high priority public health issue for national governments. Neuraminidase inhibitors are thought to help reduce the symptoms of influenza with several possible ...


A study has found Telaprevir ( VX-950; Incivek, Incivo ), a protease inhibitor, combined with standard hepatitis C treatment, cures a significantly higher number of difficult-to-treat patients th ...


A study to assess the adverse effects of anti-retroviral drugs has shown that two widely-used HIV drugs are associated with an increased risk of myocardial infarction and formation of blood clots in t ...


Even with effective anti-HIV therapies, physicians still have not been able to eradicate the virus from infected individuals who are receiving such treatments, largely because of the persistence of HI ...


Studies 102 and 103 have compared Viread ( Tenofovir disoproxil ) to Hepsera ( Adefovir dipivoxil ) among patients with HBeAg-negative chronic hepatitis B and patients with HBeAg-positive hepatitis B, ...