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Results from a phase 1 study evaluating the pharmacokinetics and safety of a prototype subdermal drug-eluting implant for extended administration of Islatravir, a nucleoside reverse transcriptase tran ...


Week 48 results from phase III TANGO study were announced. The TANGO study was conducted to assess whether adults living with HIV-1 who had maintained viral suppression for at least six months on a Te ...


Integrase strand transfer inhibitor ( INSTI ) resistance profiles and factors associated with resistance in antiretroviral-naive and -experienced patients failing an INSTI-based regimen in clinical pr ...


The aim of a study was to expand understanding of the virological potency of initial Dolutegravir plus Lamivudine dual therapy ( Dolutegravir / Lamivudine; Dovato ). Researchers have compared the vir ...


The FDA ( US Food and Drug Administration ) has approved a new drug for the treatment of influenza. Baloxavir marboxil ( Xofluza ) works against the two types of influenza virus that cause disease in ...


Immunotherapy has been a major breakthrough in oncology, but little is known about its safety for HIV-positive cancer patients. A study, presented at the ESMO 2018 Congress in Munich, has now provid ...


The results from a multi-arm phase 2 clinical trial evaluating Grazoprevir / Elbasvir ( MK-5172 / MK-8742, the investigational NS3/4A protease inhibitor and NS5A inhibitor, respectively ) with or wit ...


Data from the ALLY trial investigating a Ribavirin-free 12-week regimen of Daclatasvir ( DCV ) in combination with Sofosbuvir ( SOF ) in genotype 3 hepatitis C ( HCV ) patients, a patient population t ...


Results from studies in chronic hepatitis C patients with human immunodeficiency virus type 1 ( HIV-1 ) co-infection ( TURQUOISE-I ) and liver transplant recipients ( CORAL-I ) were presented at The L ...


A commonly-used HIV drug has been shown to kill off the human papillomavirus ( HPV ) that leads to cervical cancer in a world-first clinical trial. Researchers have examined Kenyan women diagnosed w ...


Researchers have successfully treated the deadly Ebola virus in infected animals following onset of disease symptoms, according to a report published in Science Translational Medicine. The results s ...


Short-course antiretroviral therapy ( ART ) in primary human immunodeficiency virus ( HIV ) infection may delay disease progression but has not been adequately evaluated.Researchers randomly assigned ...


Interim data presented recently have shown that all patients ( 13/13 ) who reached their 4-weeks post-treatment follow-up have undetectable levels of hepatitis C virus ( SVR4 ) after completing a 12-w ...


Planning for outbreaks of influenza is a high priority public health issue for national governments. Neuraminidase inhibitors are thought to help reduce the symptoms of influenza with several possible ...


A study has found Telaprevir ( VX-950; Incivek, Incivo ), a protease inhibitor, combined with standard hepatitis C treatment, cures a significantly higher number of difficult-to-treat patients th ...